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Executive Summary

Background
This independent study uniquely compares the ROIs of four leading industry promotional tactics. The research was conducted by Dr. Scott Neslin (Albert Wesley Fry Professor of Marketing, Amos Tuck School of Business, Dartmouth College) under an unrestricted educational grant by the Association of Medical Publications (AMP). Data were provided by Scott-Levin and PERQ/HCI directly to Dr. Neslin.


Study Objectives
To measure the ROIs for detailing (DET), direct-to-consumer advertising (DTC), medical journal advertising (JAD), and physician meetings & events (PME)
To understand how the ROIs differ according to brand size ($25-$50 million, $50-$200 million, $200+ million) and launch date (£1993, 1994-1996, 1997-1999)


Overall Approach
Used historical data (the benefit being that this is not an experiment, but reality in the marketplace)
Analyzed the data using a standard statistical technique (ordinary least squares regression)
Regression analysis examines all the brands in all the months in which they were marketed. It then analyzes how changes in expenditures over time correlate with changes in script levels over time. Regression will conclude that a marketing variable has a high ROI if that variable can consistently explain changes in script levels
Evaluated the data in aggregate to calculate the ROIs for:
Overall median brand profile
Median brand profile according to brand size/launch date


Data
Evaluated 391 drugs (all brands with 3$25MM in revenues in 1999)
Covered the time period 1995-1999
Yielded a total of 16,696 monthly observations


Results

Overall median brand profile ROI:
 
ROI
Margin of Error
(95% confidence)
DET $1.72 ±$0.19
DTC $0.19 ±$0.52
JAD $5.00 ±$0.88
PME $3.56 ±$1.92


Median Brand Profile ROI by Size/Launch Date:
DET Year of Launch
  1993 1994-1996 1997-1999
$25-$50MM $1.27 $1.41 $1.45
$50-$200MM $1.78 $2.68 $3.70
$200+MM $2.34 $6.76 $10.29


DTC Year of Launch
  1993 1994-1996 1997-1999
$25-$50MM n.s. n.s. $0.25
$50-$200MM n.s. $0.43 $0.59
$200+MM n.s. n.s. $1.37


JAD Year of Launch
  1993 1994-1996 1997-1999
$25-$50MM $3.50 $2.58 $2.22
$50-$200MM $5.29 $4.54 $4.47
$200+MM $6.79 $6.86 $5.42
n.s. = not statistically different from zero, two-tailed test, 0.05 significance level.


Conclusions
Detailing (DET)
Overall ROI of $1.72 suggests that DET pays off even at very high levels of expenditure
DET had a wide range of ROIs ($1.27-$10.29), depending on brand size/launch date
ROI for DET was higher for large and more recently launched brands

Direct-to-Consumer Advertising (DTC)
DTC ROI ranged up to $1.37, depending on brand size/launch date
DTC was most effective for large and more recently launched brands

Medical Journal Advertising (JAD)
JAD's overall ROI of $5.00 was the highest among the four marketing variables evaluated
JAD's high ROI, plus its small share of total promotional budget, suggests that JAD is underutilized
ROI for JAD spanned $2.22-$6.86, depending on brand size/launch date
ROI for JAD was higher for larger and older brands

Physician Meetings & Events (PME)
PME's overall ROI of $3.56 was second highest
PME's high ROI, plus its small share of total promotional budget, suggests that PME is underutilized



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